Molecular Virology Lead Scientist

Cape Fox Shared Services

Mar 07, 2025
Molecular Virology Lead Scientist Work Location: Fort Detrick, MD Eagle Health is seeking a Molecular Virology Lead Scientist to join our team in Fort Detrick, MD. Core Duties: Serve as a Research Investigator within the Molecular Virology Branch, primarily assisting with research aimed at the discovery and development of medical countermeasures targeting viruses that pose a threat to the military and require high containment Work in BSL-2, BSL-3, and BSL-4 laboratories and must hold and maintain Biological Personnel Reliability Program (BPRP) status, in accordance with (IAW) the provisions of this contract and applicable regulations Work with controlled substances and must hold and maintain CS-PRP status, IAW the provisions of this contract and applicable regulations Perform research on emerging viruses, in particular viruses in the Bunyavirales Order, in BSL-3 and BSL-4 containment; research areas include medical countermeasure development, molecular virology, host responses to viral infection, and pathogenesis Contribute to the design and conduct of research projects, analyze data elucidating complex mechanisms of host-viral interaction for viruses of military importance, and report findings to technical point of contact (TPOC) and laboratory team Coordinate and collaborate with scientists within the Division and the Institute on in vivo, in vitro, and ex vivo studies to evaluate medical countermeasures against infectious diseases and analyze the data from these studies, report the data to the PI, and assist in planning next step studies Contribute to the writing of animal protocols for submission and approval by the Institutional Animal Care and Use Committee (IACUC) Support animal studies by administering anesthesia and performing phlebotomy, necropsy, and treatment on small animals infected with BSL-3 and BSL-4 viruses and plot data from these studies, report to the PI, and assist in planning next step studies Independently perform and analyze Nanostring assays, interpret data based on understanding complex cellular signaling pathways, and assist in planning and executing confirmatory experiments Independently perform and analyze Luminex-based platform assays and develop novel assays based on Luminex platform for antigen or antibody detection Perform immunological procedures to characterize antibody responses including, but not limited to, enzyme-linked immunoassay (ELISA), Western Blot, flow cytometry, plaque reduction neutralization test (PRNT), and immunohistochemistry (ICH) Assist in the preparation of BSL-2, BSL-3, and BSL-4 labs for Safety, Bio-surety, CDC, and Department of Army Inspector General inspections at a minimum of four (4) times per year Seek funding from the Defense Threat Reduction Agency (DTRA) and other funding agencies in collaboration with the Government and USAMRIID to further the research portfolio of the Division and USAMRIID Assist in the preparation of grants and proposals, submitting a minimum of three proposals for prospective funding opportunities per year to the institute's portfolio management committee or equivalent for consideration Prepare technical reports describing the status of projects to appropriate funding agencies, quarterly or as defined by the reporting requirements of the department, division, and funding sponsor Author manuscripts related to research findings and submit for publication in relevant scientific journals; at least one first author manuscript and 1-2 contributing author manuscript will be submitted each year Present research findings at least one scientific conference per year, if required, which may require CONUS and/or OCONUS travel and will present results in written and oral format publicly and internally Serve as a BSL-2, BSL-3, and BSL-4 mentor Provide the TPOC with a PI Technical Report no later than (NLT) the last working day of each month BPRP and CS-PRP enrollment are required and will be held and maintained IAW the provisions in this contract and all applicable regulations