Principal Product Manager, CS CoE Informatics Operations

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Advances in AI, data, and computational sciences are transforming drug discovery and development. Roche's Research and Early Development organisations at Genentech (gRED) and Pharma (pRED) have demonstrated how these technologies accelerate R&D, leveraging data and novel computational models to drive impact. Seamless data sharing and access to models across gRED and pRED are essential to maximising these opportunities. The Computational Sciences Center of Excellence (CS-CoE) is a strategic, unified group whose goal is to harness this transformative power of data and Artificial Intelligence (AI) to assist our scientists in both pRED and gRED to deliver more innovative and transformative medicines for patients worldwide.

The gRED Computational Sciences CoE Portfolio & Operations group seeks a versatile and motivated Product Manager to drive product vision, strategy, and delivery of technology-enabled solutions and services that support and transform our Informatics Operations portfolio. This position requires a leader who can operate at both strategic and tactical levels-shaping roadmaps, engaging stakeholders, and ensuring execution excellence while combining deep operational understanding with strong product management leadership. The ideal candidate has experience bridging research operations, business operations, and informatics, with proven ability to manage product lifecycles, facilitate agile development, prioritize complex portfolios, and influence across functions.

The Opportunity:

• Define and communicate the vision, strategy, and roadmap for digital and operational products.

• Manage product lifecycles end-to-end from ideation through launch, adoption, and continuous improvement.

• Oversee product portfolio prioritization and planning, balancing business impact, customer value, scalability, delivery cost and effort.

• Partner with stakeholders to gather requirements, prioritize needs, and translate user goals into actionable product features.

• Conduct risk analysis, compliance reviews, and budget planning as needed.

• Monitor product performance using key metrics and adjust roadmaps accordingly.

• Build trusted relationships with stakeholders across Research and Business Operations groups, Computational Sciences, Global Informatics, and other business partners.

• Clearly communicate progress, risks, and impacts to leadership and stakeholders.

• Develop product materials and spearhead adoption efforts to maximize product value.

• Lead cross-functional product teams spanning operations, informatics, and science to deliver impactful solutions and services.

• Foster a collaborative culture that values diverse perspectives and continuous learning.

• Identify and promote emerging technologies and best practices in operations, digital platforms, AI, and automation.

Who You Are:

• Bachelor's degree in a technology, operations, or science discipline; advanced degree preferred.

• 8+ years in product management, IT business analysis, or related roles; prior experience in research operations strongly preferred.

• Proven ability to define product strategy, build roadmaps, and deliver solutions in complex environments.

• Familiarity with scientific applications, lab operations systems, and digital platforms.

• Strong interpersonal and communication skills, able to engage effectively with both technical and non-technical stakeholders.

• Experience with agile methodologies, requirements management, and user-centered design; certification in an agile delivery framework (e.g., Scrum Alliance, SAFe, or equivalent) is a plus.

• Demonstrated ability to balance strategic thinking with hands-on delivery.

Onsite presence, on our South San Francisco campus, is expected for at least 3 days a week.

Relocation benefits are available for this job posting.

The expected salary range for this position based on the primary location of California is $148,600 - $276,000 of hiring range. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance. This position also qualifies for the benefits detailed at the link provided below.

Benefits

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Genentech is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

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