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New

Principal Software Engineer

Roche Holdings Inc.
$162,600-$302,000
relocation assistance
United States, California, Santa Clara
2801 Scott Boulevard (Show on map)
Sep 10, 2025

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.

The Position

A healthier future. It's what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That's what makes us Roche.

Roche Sequencing is developing ground-breaking next-generation sequencing products that allow scientists/clinicians powerful new avenues to investigate DNA, the blueprint of any lifeforms, in days giving them the ability to understand health conditions such as cancer, HIV, COVID19 and more! We are not only changing science but changing lives through the development of frontier technologies that accelerate personalized healthcare.

The Opportunity:

  • Analyzes, designs and develops requirements of long-term, complex software applications in accordance with overall project goals.

  • Develops, modifies, and re-configures software methodologies for product line applications.

  • Conducts risk analysis and assessment of complex, integrated software projects.

  • Conducts systems level analysis of software to include requirements, design, testing, modifications, planning, scheduling cost, and performance.

  • Receives input from technical team members and incorporates project recommendations.

  • Prepares documentation and reports, and makes technical recommendations to program management and team members.

  • Develops and provides input for proposal activities to include technical analysis, project requirements, performance, scheduling, and costs.

  • Develops software systems performance metrics and project standards in accordance with complete project goals and commitments.

Who You Are:

  • You have a BS/BA degree in Computer Science, Science or Engineering or a related field

  • You have 8+ years of Python, Angular, C++/Object-oriented programming, software architecture, networking, and distributed systems, and/or UNIX/NT development

  • You have 8+ years of experience in Cloud Platforms including Compute, Storage, Kubernetes, Notification systems, managed services, security, encryption, networking, orchestration, and optimization

  • You have 8+ years of experience database applications and real time systems

  • You have 8+ years of experience handling Big Data

  • You have experience in a combination of the following: Database applications, graphic applications, real-time systems, numerical analysis, networks, modeling, simulation, systems management, expert systems and/or system tests.

  • You have knowledge of software engineering concepts, principles and languages applicable to the product line supporting

  • You have general knowledge of computer aided software engineering principles and systems

  • You have knowledge of structure analysis techniques

  • You have Information Security and Data Privacy fundamentals

  • You have a good understanding of git with GitHub or similar platforms and CI/CD environments

Preferred Qualifications:

  • You have Google Cloud Platform experience

The expected salary range for this position based on the primary location of Primary Location State is Santa Clara, CA is: $162,600-$302,000. Actual pay will be determined based on experience, qualifications, geographic location, and other job-related factors permitted by law. A discretionary annual bonus may be available based on individual and Company performance.

This position also qualifies for the benefits detailed at the link provided below. Benefits

This position will not provide relocation assistance

Who we are

A healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.

Let's build a healthier future, together.

Roche is an equal opportunity employer. It is our policy and practice to employ, promote, and otherwise treat any and all employees and applicants on the basis of merit, qualifications, and competence. The company's policy prohibits unlawful discrimination, including but not limited to, discrimination on the basis of Protected Veteran status, individuals with disabilities status, and consistent with all federal, state, or local laws.

If you have a disability and need an accommodation in relation to the online application process, please contact us by completing this form Accommodations for Applicants.

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