Postdoctoral Associate | Cardiac Physiology & Molecular Biology

Hinson Lab - Farmington, CT

The Hinson Lab is seeking an independent, highly motivated PhD-level scientist to join our group at The Jackson Laboratory for Genomic Medicine and UConn Health. Our research combines mouse models of cardiovascular disease, advanced cardiac physiology approaches, and molecular biology techniques to investigate the mechanisms of cardiomyopathy and heart failure.

The ideal candidate will bring strong expertise in mouse handling and procedures, in vivo/ex vivo cardiac functional assays, and molecular biology methods. Experience with human iPSC-based cardiac models is considered an advantage but is not required.

Key Responsibilities

• Perform mouse handling, survival procedures, and tissue collection.
• Conduct mouse echocardiography and other in vivo cardiac functional assessments.
• Apply ex vivo cardiac physiology techniques, including IonOptix systems for contractility and calcium handling studies.
• Contribute to AAV production and viral vector-based gene delivery.
• Perform molecular and cell biology assays, including PCR, cloning, Western blotting, and mammalian cell culture.
• Maintain rigorous documentation, analyze data, and contribute to manuscripts and grant applications.
• Collaborate within a multidisciplinary research team spanning physiology, molecular biology, and computational biology.

Preferred/Bonus Skills

• Experience with human iPSC-derived cardiomyocytes and engineered cardiac microtissues.
• Familiarity with iPSC differentiation, culture, functional assays, and genome editing.

Qualifications

• PhD in Physiology, Molecular Biology, Genetics, Biomedical Engineering, or a related field.
• Prior research experience in mouse/rodent models of cardiovascular disease and cardiac physiology is strongly preferred.
• Strong publication record in peer-reviewed journals.
• Excellent communication and teamwork skills, with the ability to work independently and collaboratively.
• Familiarity with statistical and bioinformatics tools (e.g., R, Python) is advantageous.

Application Instructions:
Please submit your current CV, at least 2 letters of reference, and a 1-page (maximum) statement of Research Interests and Career Goals at the time of application.

We are a diverse and inclusive research group, aspiring to produce top science and scientists through attentive and progressive mentoring and interdisciplinary teamwork.

JAX Postdoc Salary:

Year 0 - 1: $65,589

Year 1 - 2: $67,318

Year 2 - 3: $69,095

Year 3 - 4: $70,521

Year 4 - 5: $72,877

Year 5 - 6: $75,569

Based on years of experience as Postdoc.

About JAX:

The Jackson Laboratory is an independent, nonprofit biomedical research institution with a National Cancer Institute-designated Cancer Center and nearly 3,000 employees in locations across the United States (Maine, Connecticut, California),Japan andChina. Its mission is to discover precise genomic solutions for disease and empower the global biomedical community in the shared quest to improve human health.

Founded in 1929, JAX applies over nine decades of expertise in genetics to increase understanding of human disease, advancing treatments and cures for cancer, neurological and immune disorders, diabetes, aging and heart disease. It models and interprets genomic complexity, integrates basic research with clinical application, educates current and future scientists, and provides critical data, tools and services to the global biomedical community. For more information, please visitwww.jax.org.

EEO Statement:

The Jackson Laboratory provides equal employment opportunities to all employees and applicants for employment in all job classifications without regard to race, color, religion, age, mental disability, physical disability, medical condition, gender, sexual orientation, genetic information, ancestry, marital status, national origin, veteran status, and other classifications protected by applicable state and local non-discrimination laws.