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Post Doctoral Fellow Lung Fibrosis

Massachusetts General Hospital
United States, Massachusetts, Boston
55 Fruit Street (Show on map)
Oct 07, 2025
Postdoctoral position available to study mechanisms of vascular biology, lung injury and lung fibrosis in the Division of Pulmonary and Critical Care Medicine at Massachusetts General Hospital and Harvard Medical School. The Knipe Lab is looking for a hard-working and enthusiastic post-doctoral candidate to work on a funded project investigating mechanisms of endothelial cell dysfunction in the context of fibrosis in the lungs. We are interested in strategies to improve endothelial function in the context of fibrotic lung diseases like scleroderma associated ILD and idiopathic pulmonary fibrosis (IPF). This project involved both animal modeling of lung disease (mice) and in vitro cell culture work with human microvascular endothelial cells.

We are seeking a highly motivated, independent, innovative, and organized individual with an interest in translational biomedicine for this Post-Doctoral Research Fellow position. The appropriate candidate will work in a highly collaborative research environment that aims to define the role of endothelial dysfunction and vascular permeability in the development of fibrosis. The position will involve (but not be limited to) planning and conducting in vivo mouse modeling of pulmonary fibrosis, ex vivo and in vitro cell culture experiments, histology and microscopy including widefield and confocal imaging, molecular biology techniques to analyze RNA and protein expression in cells and tissues, and sequencing (both bulk and single cell opportunities).

The project is well-situated to generate high impact publications, presentations at conferences and prepare the post-doc for a long-term career in academia or industry. Applicants with prior post-doctoral experience are encouraged to apply. This position is NIH funded starting in 2025 for two years.

All interested candidates are encouraged to submit their CV/resume accompanied by a cover letter describing prior research experience to Dr. Knipe (rknipe@mgh.harvard.edu).

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The General Hospital Corporation is an Equal Opportunity Employer. By embracing diverse skills, perspectives and ideas, we choose to lead. All qualified applicants will receive consideration for employment without regard to race, color, religious creed, national origin, sex, age, gender identity, disability, sexual orientation, military service, genetic information, and/or other status protected under law. We will ensure that all individuals with a disability are provided a reasonable accommodation to participate in the job application or interview process, to perform essential job functions, and to receive other benefits and privileges of employment.
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