Postdoctoral Associate - The Hwang Lab

The Hwang laboratory at the Broad Institute of MIT & Harvard is seeking a highly motivated postdoctoral associate to investigate the mechanisms of organ dysfunction and immune paralysis in sepsis using clinical samples and animal models.

Sepsis is defined as life-threatening organ dysfunction caused by a dysregulated host response to infection. Despite considerable advances over the last decades, sepsis is still a leading cause of death in intensive care units, and survivors develop prolonged immune paralysis leading to a high incidence of recurrent infections. In the absence of definitive therapy, physicians rely on supportive care. Our team is devoted to deep understanding of immune dysfunction in sepsis for novel therapeutic hypotheses, through close collaboration with Harvard teaching hospitals.
The applicant will be expected to work well in a multi-institutes collaboration setting, communicate effectively, and possess a strong desire to contribute to basic and translational research. Training and expertise in immunology and microbiology are essential. This opportunity is particularly suited for candidates who are passionate about researching on host-pathogen interaction in systemic inflammation and metabolism settings during severe infection like sepsis.

Key Responsibilities:

• Work independently and with team members to design and carry out experiments essential to the individual project and the group's collective success.
• Consult the literature, supervisor, and other scientific staff as needed to troubleshoot experiments.
• Investigate, learn, and develop new methods and technologies that might be relevant to the project.
• Maintain and share detailed experimental records, documentation, and written protocols with team members with team members.
• Contribute to grants, papers, and patents.

Required Skills:

• PhD in cell biology, molecular biology, microbiology, immunology, or a closely related field.
• Records of leading projects successfully through publications in scientific journals and presentations in scientific conferences.
• Solid understanding and hands-on experiences in cell biological and immunological assays, investigating primary immune cells in ex vivo and in vivo setting.
• Experiences in molecular/biochemical investigation of cellular metabolism is a big plus.
• Excellent communication (oral and written) and wet lab skills, organization, and time management skills.
• High level of initiative and motivation; ability to work independently and with a team.
• Strong desire to learn new methods and ability to think creatively to solve problems.

The expected base pay range for this position as listed above is based on a 40 hour per week schedule. Broad provides pay ranges representing its reasonable and good faith estimate of what the organization reasonably expects to pay for a position at the time of posting. Actual compensation will vary based on factors including but not limited to, relevant skills, experience, education, qualifications, and other factors permissible by law.

At Broad, your base pay is just one part of a comprehensive total rewards package. From day one, this role offers a competitive benefits package including medical, dental, vision, life, and disability insurance; a 401(k) retirement plan; flexible spending and health savings accounts; at least 13 paid holidays; winter closure; paid time off; parental and family care leave; and an employee assistance program, among other Broad benefits.

The Broad Institute is an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, national origin, religion, age, color, sex, disability, protected veteran status, or any other characteristic protected by local, state, or federal laws, rules, or regulations.

Should you need a reasonable accommodation to complete the application or interview process, please contact recruiting@broadinstitute.org for assistance.