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Research Scientist

California Institute of Technology
vision insurance, parental leave, paid time off, sick time, tuition reimbursement
United States, California, Pasadena
Aug 22, 2026

Caltech is a world-renowned science and engineering institute that marshals some of the world's brightest minds and most innovative tools to address fundamental scientific questions. We thrive on finding and cultivating talented people who are passionate about what they do. Join us and be a part of the diverse Caltech community.

Job Summary

The candidate will study the molecular mechanism of mitochondrial protein biogenesis in human cells.

Essential Job Duties

  • Structural analysis of mitochondrial membrane proteins.
  • Development of fluorescent and luminescence-based assays for mitochondrial protein biogenesis.
  • Protein purification for structural and biochemical analysis.
  • Prepare research reports, drafts and presentations for internal meetings, publications, grant proposals and conferences.

Basic Qualifications

  • PhD in molecular biology and/or biochemistry.
  • 3+ years of experience in single particle cryo-EM data collection, data processing, and model building.
  • 3+ years of experience in reconstitution of mitochondrial membrane protein biogenesis in vitro.
  • Experience in development of high throughout assays for mitochondrial protein biogenesis using both fluorescent and luminescence-based screening approaches.
  • Experience in tissue culture of diverse mammalian cell types.
  • 3+ years of experience in protein purification of membrane proteins from human, insect, and E.coli cells.

Required Documents

  • Resume.
Hiring Range

$59,800 - $76,000 Per Year

The salary of the finalist(s) selected for this role will be set based on a variety of factors, including but not limited to, internal equity, experience, education, specialty and training.

As one of the largest employers in Pasadena, CA, Caltech is committed to providing comprehensive benefits to eligible employees and their eligible dependents. Our benefits package includes competitive compensation, health, dental, and vision insurance, retirement savings plans, generous paid time off (vacation, holidays, sick time, parental leave, bereavement, etc.), tuition reimbursement, and more. Non-benefit eligible employees will have access to some benefits such as onsite counseling and sick time. Learn more about our benefits and staff perks.


EEO Statement

We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to age, race, color, religion, sex, sexual orientation, gender identity, or national origin, disability status, protected veteran status, or any other characteristic protected by law.

Caltech is a VEVRAA Federal Contractor.

To read more Equal Employment Opportunity (EEO) go to eeoc_self_print_poster.pdf.

Disability Accommodations

Caltech complies with the Fair Employment and Housing Act (FEHA) and the Americans with Disabilities Act (ADA). We consider reasonable accommodation measures that may be necessary for eligible applicants and employees to perform the essential functions of a position.

If you would like to request an accommodation to complete this application, interview, or otherwise participate in the employee selection process, please contact Caltech Recruiting at employment@caltech.edu.

Additionally, if you do not meet the basic qualifications of a role but believe you can perform the essential functions of the job with reasonable accommodation, please reach out to Caltech Recruiting at employment@caltech.edu.


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