Scientist

Spectraforce Technologies
sick time, 401(k)
United States, California, Irvine
Nov 05, 2024
Description: Job Title: Scientist Duration: 12 months (potential extension) Location: Irvine, CA, 92612 Experience Level = 1-3 Years Purpose : The successful candidate for this position will work independently and as part of a team to contribute expertise to projects aimed at designing, developing, and optimizing novel in vitro complex cell models that mimic physiological or pathological conditions and enable the study of various biological processes as well as facilitating compound screening efforts. This role requires expertise in cell and organ culture techniques, stem cell culture and induced cell differentiation, tissue engineering, and a strong background in molecular biology. Additionally, the candidate will participate and conduct in vitro assay development work to support discovery research projects and target validation studies in diseases of hair and skin. This individual will organize, analyze, and interpret results, and make recommendations based on experimental findings. Responsibilities : * Design and optimize protocols for the efficient and reproducible differentiation of iPSCs into specific cell types. * Characterize and validate the differentiated cells using molecular and functional assays to ensure their fidelity and functionality. * Develop and optimize advanced cell models, including co-culture systems, organoids, or tissue-on-a-chip platforms, using iPSC-derived cells to mimic physiological or disease conditions. * Optimize cell culture protocols, media formulations, and growth conditions to ensure the viability, functionality, and reproducibility of the developed cell models. * Work in a team environment and coordinate the design, development, and optimization of in vitro assays to support discovery research projects and target validation studies related to hair and skin diseases. * Collaborate with cross-functional teams, including biologists, engineers, and data scientists, to integrate the developed cell models into larger research projects, including supporting in vivo model development and in vivo studies * Plan experimental approaches with supervisory guidance. Discuss, recommend, and modify experimental techniques as needed. * Document and interpret results in order to reach conclusions, discuss with supervisor and decide on subsequent experiments. * Prepare technical reports, presentations, and appropriate documentation of work performed. Assist supervisor in maintaining project documentation. * Attend and participate in lab, team and departmental meetings. Presentation of data as required. Qualifications : * Proven experience in, and proficiency in iPSC maintenance, reprogramming, and differentiation techniques using various differentiation protocols are required * Proficiency in advanced cell culture techniques, including iPSC culture and differentiation, primary cell isolation, immortalized cell lines, three-dimensional (3D) cell culture systems, co-culture systems and organoid culture systems * Experience in characterizing and validating differentiated cells using functional assays and molecular markers. * Proven experience in molecular biology techniques for analysis of in vitro cell-based assays and ex vivo tissues and/or fluid (RNA isolation, qPCR, western blot, ELISA, Luminex, F/ISH, IHC, flow cytometry etc) * Proficient in data analysis software suites (e.g, GraphPad PRISM, Excel, R, etc.) * Excellent problem-solving skills and the ability to troubleshoot technical issues independently. * Strong organizational skills and attention to detail to maintain accurate records and documentation. Education: Bachelor's Degree or equivalent education, or Master's Degree or equivalent education with years of experience. Theoretical and practical knowledge to carry out the job functions. About Us: Established in 2004, SPECTRA FORCE is one of the largest and fastest-growing diversity-owned staffing firms in the US. The growth of our company is a direct result of our global client service delivery model that is powered by our state-of-the-art A.I. proprietary talent acquisition platform, robust ISO 9001:2015/ISO 27001 certified processes, and strong and passionate client engaged teams. We have built our business by providing talent and project-based solutions, including Contingent, Permanent, and Statement of Work (SOW) services to over 140 clients in the US, Canada, Puerto Rico, Costa Rica, and India. Key industries that we service include Technology, Financial Services, Life Sciences, Healthcare, Telecom, Retail, Utilities and Transportation. SPECTRA FORCE is built on a concept of "human connection," defined by our branding attitude of NEWJOBPHORIA, which is the excitement of bringing joy and freedom to the work lifestyle so our people and clients can reach their highest potential. Learn more at: http://www.spectraforce.com Benefits: SPECTRA FORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRA FORCE provides unpaid leave as well as paid sick leave when required by law. Equal Opportunity Employer: SPECTRA FORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation. California Applicant Notice: SPECTRA FORCE is committed to complying with the California Privacy Rights Act ("CPRA") effective January 1, 2023; and all data privacy laws in the jurisdictions in which it recruits and hires employees. A Notice to California Job Applicants Regarding the Collection of Personal Information can be located on our website. Applicants with disabilities may access this notice in an alternative format by contacting NAHR@spectraforce.com. LA County, CA Applicant Notice: If you are selected for this position with SPECTRA FORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer. At SPECTRA FORCE, we are committed to maintaining a workplace that ensures fair compensation and wage transparency in adherence with all applicable state and local laws. This position's starting pay is: $31.00/hr.