Postdoctoral Research Associate

The Rector & Visitors of the University of Virginia
United States, Virginia, Charlottesville
1215 Lee Street (Show on map)
Nov 20, 2024
The University of Virginia (UVA) seeks a Postdoctoral Research Associate position in the laboratory of Bon Trinh. Ph.D., Tenure-track Assistant Professor of Pathology and UVA Comprehensive Cancer Center. The broad areas of interest in Dr. Trinh's lab include: gene regulation by RNAs and proteins, modulation of gene-specific chromatin architecture, blood development, cancer and genetic diseases, therapeutic development. His lab employs a multidisciplinary approach, comprising biochemistry and cellular biology as well as global transcriptomic, epigenomic, and 3D chromatin structure analyses, using normal and cancer cells, and mouse models. Research in the Trinh lab centers on protein- and RNA- mediated gene regulation via modulating chromatin architecture in development of immune cells, particularly myeloid cells, a critical component of the body defense against infections, and how abnormalities in this regulation contribute to failure in myeloid cell maturation resulting in acute myeloid leukemia. The lab also investigates this molecular coordination in drug resistance and immune cell-cancer cell communications within the tumor microenvironment. The aims are to provide critical mechanistic insights into normal and malignant hematopoiesis, and to establish certain protein-RNA hubs as actionable therapeutic targets and molecular markers, contributing to the emerging field of precision medicine. To learn more, please visit: https://tinyurl.com/trinhlaboratory The successful candidate will join an interdisciplinary research group in which research questions and novel ideas are valued and examined from experimental and computational angles. The candidate will have opportunities to drive his/her own research project(s), develop fellowship applications, write manuscripts, mentor junior trainees, and learn skills of interest along the way. For questions regarding this position, please contact Dr. Bon Trinh via email at: bontrinh@virginia.edu. Postdoctoral employment is temporary and is normally limited to an individual who has been awarded a Ph.D. or equivalent doctorate within the previous five years1 and who will be involved in full-time research or scholarship at the University. Employment as a Postdoctoral Research Associate is viewed as training and is preparatory for a full-time academic or research career, is supervised by a senior scholar, and allows the appointee to publish the results of his/her research or scholarship during the training period. Full-time research or scholarship at the University. Preparatory for a full-time academic or research career Supervised by a senior scholar, and allows the appointee to publish the results of his/her research or scholarship In addition to the above job responsibilities, other duties may be assigned. MINIMUM REQUIREMENTS Education: Doctoral degree Experience: None Licensure: None PHYSICAL DEMANDS This is primarily a sedentary job involving extensive use of desktop computers. The job does occasionally require traveling some distance to attend meetings, and programs. The University of Virginia, including the UVA Health System which represents the UVA Medical Center, Schools of Medicine and Nursing, UVA Physician's Group and the Claude Moore Health Sciences Library, are fundamentally committed to the diversity of our faculty and staff. We believe diversity is excellence expressing itself through every person's perspectives and lived experiences. We are equal opportunity and affirmative action employers. All qualified applicants will receive consideration for employment without regard to age, color, disability, gender identity or expression, marital status, national or ethnic origin, political affiliation, race, religion, sex, pregnancy, sexual orientation, veteran or military status, and family medical or genetic information.